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The structural organization of substrate loading in iterative polyketide synthases
Polyketide synthases (PKSs) are microbial multienzymes for the biosynthesis of biologically potent secondary metabolites. Polyketide production is initiated by the loading of a starter unit onto an integral acyl carrier protein (ACP) and its subsequent transfer to the ketosynthase (KS). Initial subs...
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| Publicado no: | Nat Chem Biol |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196715/ https://ncbi.nlm.nih.gov/pubmed/29610486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0026-3 |
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