Structure–Activity Relationships of Quinoxaline-Based 5-HT(3)A and 5-HT(3)AB Receptor-Selective Ligands

Until recently, discriminating between homomeric 5-HT(3)A and heteromeric 5-HT(3)AB receptors was only possible with ligands that bind in the receptor pore. This study describes the first series of ligands that can discriminate between these receptor types at the level of the orthosteric binding sit...

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書誌詳細
主要な著者: Thompson, Andrew J, Verheij, Mark H P, van Muijlwijk-Koezen, Jacqueline E, Lummis, Sarah C R, Leurs, Rob, de Esch, Iwan J P
フォーマット: Artigo
言語:Inglês
出版事項: WILEY-VCH Verlag 2013
主題:
Full Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063337/
https://ncbi.nlm.nih.gov/pubmed/23640722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300032
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