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A single channel mutation alters agonist efficacy at 5-HT(3)A and 5-HT(3)AB receptors

BACKGROUND AND PURPOSE: 5-HT(3) receptors are composed of 5-HT(3)A subunits (homomeric receptors), or combinations of 5-HT(3)A and other 5-HT(3) receptor subunits (heteromeric receptors, the best studied of which are 5-HT(3)AB receptors). Here we explore the effects of partial agonists at 5-HT(3)A a...

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Detalhes bibliográficos
Main Authors: Thompson, A J, Lummis, S C R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834762/
https://ncbi.nlm.nih.gov/pubmed/23822584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12287
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