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Agonists and Antagonists Bind to an A-A Interface in the Heteromeric 5-HT(3)AB Receptor

The 5-HT(3) receptor is a member of the Cys-loop family of transmitter receptors. It can function as a homopentamer (5-HT3A-only subunits) or as a heteropentamer. The 5-HT(3)AB receptor is the best characterized heteropentamer. This receptor differs from a homopentamer in its kinetics, voltage depen...

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Bibliographic Details
Main Authors: Lochner, M., Lummis, S.C.R.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856171/
https://ncbi.nlm.nih.gov/pubmed/20409468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4313
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