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Discriminating between 5-HT(3)A and 5-HT(3)AB receptors

The 5-HT3B subunit was first cloned in 1999, and co-expression with the 5-HT3A subunit results in heteromeric 5-HT(3)AB receptors that are functionally distinct from homomeric 5-HT(3)A receptors. The affinities of competitive ligands at the two receptor subtypes are usually similar, but those of non...

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Bibliographic Details
Main Authors: Thompson, AJ, Lummis, SCR
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687655/
https://ncbi.nlm.nih.gov/pubmed/23489111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12166
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