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VUF10166, a Novel Compound with Differing Activities at 5-HT(3)A and 5-HT(3)AB Receptors
The actions of a novel, potent 5-HT(3) receptor ligand, [2-chloro-(4-methylpiperazine-1-yl)quinoxaline (VUF10166)], were examined at heterologously expressed human 5-HT(3)A and 5-HT(3)AB receptors. VUF10166 displaced [(3)H]granisetron binding to 5-HT(3)A receptors expressed in human embryonic kidney...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3336813/ https://ncbi.nlm.nih.gov/pubmed/22306960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190769 |
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