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Agonists and antagonists induce different palonosetron dissociation rates in 5-HT(3)A and 5-HT(3)AB receptors()
Palonosetron is a potent 5-HT(3) receptor antagonist with a unique structure and some unusual properties. Here we explore the properties of palonosetron at heterologously expressed 5-HT(3)A and 5-HT(3)AB receptors. We used receptors expressed in HEK293 cells, and functionally analysed them using a m...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Pergamon Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778450/ https://ncbi.nlm.nih.gov/pubmed/23747573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2013.05.010 |
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