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Exploring a potential palonosetron allosteric binding site in the 5-HT(3) receptor()
Palonosetron (Aloxi) is a potent second generation 5-HT(3) receptor antagonist whose mechanism of action is not yet fully understood. Palonosetron acts at the 5-HT(3) receptor binding site but recent computational studies indicated other possible sites of action in the extracellular domain. To test...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3898987/ https://ncbi.nlm.nih.gov/pubmed/24128813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.09.028 |
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