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5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytes
BACKGROUND: Cytosine methylation is a frequent epigenetic modification restricting the activity of gene regulatory elements. Whereas DNA methylation patterns are generally inherited during replication, both embryonic and somatic differentiation processes require the removal of cytosine methylation a...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053946/ https://ncbi.nlm.nih.gov/pubmed/23705593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r46 |
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