Tissue Distribution of 5-Hydroxymethylcytosine and Search for Active Demethylation Intermediates

5–Hydroxymethylcytosine (hmC) was recently detected as the sixth base in mammalian tissue at so far controversial levels. The function of the modified base is currently unknown, but it is certain that the base is generated from 5-methylcytosine (mC). This fuels the hypothesis that it represents an i...

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Bibliographic Details
Main Authors: Globisch, Daniel, Münzel, Martin, Müller, Markus, Michalakis, Stylianos, Wagner, Mirko, Koch, Susanne, Brückl, Tobias, Biel, Martin, Carell, Thomas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009720/
https://ncbi.nlm.nih.gov/pubmed/21203455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015367
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