5-Hydroxymethylcytosine is an essential intermediate of active DNA demethylation processes in primary human monocytes

BACKGROUND: Cytosine methylation is a frequent epigenetic modification restricting the activity of gene regulatory elements. Whereas DNA methylation patterns are generally inherited during replication, both embryonic and somatic differentiation processes require the removal of cytosine methylation a...

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Detalhes bibliográficos
Main Authors: Klug, Maja, Schmidhofer, Sandra, Gebhard, Claudia, Andreesen, Reinhard, Rehli, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053946/
https://ncbi.nlm.nih.gov/pubmed/23705593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-5-r46
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