Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels

BACKGROUND: In mammals, the dynamics of DNA methylation, in particular the regulated, active removal of cytosine methylation, has remained a mystery, partly due to the lack of appropriate model systems to study DNA demethylation. Previous work has largely focused on proliferating cell types that are...

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Detalhes bibliográficos
Main Authors: Klug, Maja, Heinz, Sven, Gebhard, Claudia, Schwarzfischer, Lucia, Krause, Stefan W, Andreesen, Reinhard, Rehli, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911111/
https://ncbi.nlm.nih.gov/pubmed/20565882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-6-r63
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