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Methylene blue does not reverse existing neurofibrillary tangle pathology in the rTg4510 mouse model of tauopathy
Alzheimer's disease is characterized pathologically by aggregation of amyloid beta into senile plaques and aggregation of pathologically modified tau into neurofibrillary tangles. While changes in amyloid processing are strongly implicated in disease initiation, the recent failure of amyloid-ba...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992382/ https://ncbi.nlm.nih.gov/pubmed/24462887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.01.013 |
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