Purification, crystallization and preliminary crystallographic analysis of the catalytic core of cystathionine β-synthase from Saccharomyces cerevisiae

Cystathionine β-synthase (CBS; EC 4.2.1.22) catalyzes the condensation of homocysteine and serine to form cystathionine, with the release of water. In humans, deficiency in CBS activity is the most common cause of hyperhomocysteinaemia and homocystinuria. More than 160 pathogenic mutations in the hu...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2014
Gaiak:
Crystallization Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944693/
https://ncbi.nlm.nih.gov/pubmed/24598918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14001502
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