Purification, crystallization and preliminary crystallographic analysis of human cystathionine β-synthase

Human cystathionine β-synthase (CBS) is a pyridoxal-5′-phosphate-dependent hemeprotein, whose catalytic activity is regulated by S-adenosylmethionine. CBS catalyzes the β-replacement reaction of homocysteine (Hcy) with serine to yield cystathionine. CBS is a key regulator of plasma levels of the thr...

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Detalhes bibliográficos
Main Authors: Oyenarte, Iker, Majtan, Tomas, Ereño, June, Corral-Rodríguez, María Angeles, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515372/
https://ncbi.nlm.nih.gov/pubmed/23143240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112037219
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