Folding and activity of mutant cystathionine β-synthase depends on the position and nature of the purification tag: Characterization of the R266K CBS mutant

Por Majtan, Tomas, Kraus, Jan P.
Publicado em 2012

Environmental influences on familial discordance of phenotype in people with homocystinuria: a case report

Por Maillot Francois, Kraus Jan P, Lee Philip J
Publicado em 2008-04-01

Environmental influences on familial discordance of phenotype in people with homocystinuria: a case report

Por Maillot, Francois, Kraus, Jan P, Lee, Philip J
Publicado em 2008

Effect of cobalt on Escherichia coli metabolism and metalloporphyrin formation

Por Majtan, Tomas, Frerman, Frank E., Kraus, Jan P.
Publicado em 2010

The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein

Por Pey, Angel L., Majtan, Tomas, Kraus, Jan P.
Publicado em 2014

Rescue of Cystathionine β-Synthase (CBS) Mutants with Chemical Chaperones: PURIFICATION AND CHARACTERIZATION OF EIGHT CBS MUTANT ENZYMES

Por Majtan, Tomas, Liu, Lu, Carpenter, John F., Kraus, Jan P.
Publicado em 2010

Purification and characterization of the wild type and truncated human cystathionine β-synthase enzymes expressed in E. coli

Por Frank, Nina, Kent, Jana O., Meier, Markus, Kraus, Jan P.
Publicado em 2007

Structure of human cystathionine β-synthase: a unique pyridoxal 5′-phosphate-dependent heme protein

Por Meier, Markus, Janosik, Miroslav, Kery, Vladimir, Kraus, Jan P., Burkhard, Peter
Publicado em 2001

Active Cystathionine β-Synthase Can Be Expressed in Heme-free Systems in the Presence of Metal-substituted Porphyrins or a Chemical Chaperone

Por Majtan, Tomas, Singh, Laishram R., Wang, Liqun, Kruger, Warren D., Kraus, Jan P.
Publicado em 2008

Purification and characterization of cystathionine β-synthase bearing a cobalt protoporphyrin

Por Majtan, Tomas, Freeman, Katherine M., Smith, Aaron T., Burstyn, Judith N., Kraus, Jan P.
Publicado em 2011

Cross-Talk between the Catalytic Core and the Regulatory Domain in Cystathionine β-Synthase: Study by Differential Covalent Labeling and Computational Modeling

Por Hnízda, Aleš, Spiwok, Vojtěch, Jurga, Vojtěch, Kožich, Viktor, Kodíček, Milan, Kraus, Jan P.
Publicado em 2010

Long-Term Sex-Biased Correction of Circulating Propionic Acidemia Disease Markers by Adeno-Associated Virus Vectors

Por Guenzel, Adam J., Collard, Renata, Kraus, Jan P., Matern, Dietrich, Barry, Michael A.
Publicado no Hum Gene Ther (2015)

Activation of Mutant Enzyme Function In Vivo by Proteasome Inhibitors and Treatments that Induce Hsp70

Por Singh, Laishram R., Gupta, Sapna, Honig, Nicholaas H., Kraus, Jan P., Kruger, Warren D.
Publicado em 2010

Structural basis of regulation and oligomerization of human cystathionine β-synthase, the central enzyme of transsulfuration

Por Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Publicado em 2013

Purification, crystallization and preliminary crystallographic analysis of the catalytic core of cystathionine β-synthase from Saccharomyces cerevisiae

Por Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Publicado em 2014

Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine

Por Ereño-Orbea, June, Majtan, Tomas, Oyenarte, Iker, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Publicado em 2014

Impaired Heme Binding and Aggregation of Mutant Cystathionine β-Synthase Subunits in Homocystinuria

Por Janošík, Miroslav, Oliveriusová, Jana, Janošíková, Bohumila, Sokolová, Jitka, Kraus, Eva, Kraus, Jan P., Kožich, Viktor
Publicado em 2001

Cobalt Cystathionine β-Synthase: A Cobalt-Substituted Heme Protein with a Unique Thiolate Ligation Motif

Por Smith, Aaron T., Majtan, Tomas, Freeman, Katherine M., Su, Yang, Kraus, Jan P., Burstyn, Judith N.
Publicado em 2011

The Effect of the Disease-Causing R266K Mutation on the Heme and PLP Environments of Human Cystathionine β-Synthase

Por Smith, Aaron T., Su, Yang, Stevens, Daniel J., Majtan, Tomas, Kraus, Jan P., Burstyn, Judith N.
Publicado em 2012

Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria

Por Majtan, Tomas, Hůlková, Helena, Park, Insun, Krijt, Jakub, Kožich, Viktor, Bublil, Erez M., Kraus, Jan P.
Publicado no FASEB J (2017)