Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues

Por Krijt, Jakub, Dutá, Alena, Kožich, Viktor
Publicado em 2009

Restoring assembly and activity of cystathionine β-synthase mutants by ligands and chemical chaperones

Por Kopecká, Jana, Krijt, Jakub, Raková, Kateřina, Kožich, Viktor
Publicado em 2010

Novel structural arrangement of nematode cystathionine β-synthases: characterization of Caenorhabditis elegans CBS-1

Por Vozdek, Roman, Hnízda, Aleš, Krijt, Jakub, Kostrouchová, Marta, Kožich, Viktor
Publicado em 2012

Birth Prevalence of Homocystinuria in Central Europe: Frequency and Pathogenicity of Mutation c.1105C>T (p.R369C) in the Cystathionine Beta-Synthase Gene

Por Janošík, Miroslav, Sokolová, Jitka, Janošíková, Bohumila, Krijt, Jakub, Klatovská, Veronika, Kožich, Viktor
Publicado em 2009

Cystathionine β-Synthase p.S466L Mutation Causes Hyperhomocysteinemia in Mice

Por Gupta, Sapna, Wang, Liqun, Hua, Xiang, Krijt, Jakub, Kožich, Viktor, Kruger, Warren D.
Publicado em 2008

The Cysteine Dioxgenase Knockout Mouse: Altered Cysteine Metabolism in Nonhepatic Tissues Leads to Excess H(2)S/HS(−) Production and Evidence of Pancreatic and Lung Toxicity

Por Roman, Heather B., Hirschberger, Lawrence L., Krijt, Jakub, Valli, Alessandro, Kožich, Viktor, Stipanuk, Martha H.
Publicado em 2013

Cystathionine β-Synthase Mutations: Effect of Mutation Topology on Folding and Activity

Por Kožich, Viktor, Sokolová, Jitka, Klatovská, Veronika, Krijt, Jakub, Janošík, Miroslav, Jelínek, Karel, Kraus, Jan P, Cooper, David N
Publicado em 2010

Enzyme replacement with PEGylated cystathionine β-synthase ameliorates homocystinuria in murine model

Por Bublil, Erez M., Majtan, Tomas, Park, Insun, Carrillo, Richard S., Hůlková, Helena, Krijt, Jakub, Kožich, Viktor, Kraus, Jan P.
Publicado no J Clin Invest (2016)

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

Por Jurkowska, Halina, Roman, Heather B., Hirschberger, Lawrence L., Sasakura, Kiyoshi, Nagano, Tetsuo, Hanaoka, Kenjiro, Krijt, Jakub, Stipanuk, Martha H.
Publicado no Amino Acids (2014)

Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats

Por Pravenec, Michal, Kožich, Viktor, Krijt, Jakub, Sokolová, Jitka, Zídek, Václav, Landa, Vladimír, Šimáková, Miroslava, Mlejnek, Petr, Šilhavý, Jan, Oliyarnyk, Olena, Kazdová, Ludmila, Kurtz, Theodore W.
Publicado em 2013

Cystathionine beta-synthase null homocystinuric mice fail to exhibit altered hemostasis or lowering of plasma homocysteine in response to betaine treatment

Por Maclean, Kenneth N., Sikora, Jakub, Kožich, Viktor, Jiang, Hua, Greiner, Lori S., Kraus, Eva, Krijt, Jakub, Crnic, Linda S., Allen, Robert H., Stabler, Sally P., Elleder, Milan, Kraus, Jan P.
Publicado em 2010

A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine...

Por Maclean, Kenneth N., Sikora, Jakub, Kožich, Viktor, Jiang, Hua, Greiner, Lori S., Kraus, Eva, Krijt, Jakub, Overdier, Katherine H., Collard, Renata, Brodsky, Gary L., Meltesen, Lynne, Crnic, Linda S., Allen, Robert H., Stabler, Sally P., Elleder, Milan, Rozen, Rima, Patterson, David, Kraus, Jan P.
Publicado em 2010