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Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate

The oxidation of cysteine in mammalian cells occurs by two routes: a highly regulated direct oxidation pathway in which the first step is catalyzed by cysteine dioxygenase (CDO) and by desulfhydration-oxidation pathways in which the sulfur is released in a reduced oxidation state. To assess the effe...

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Detalhes bibliográficos
Publicado no:Amino Acids
Main Authors: Jurkowska, Halina, Roman, Heather B., Hirschberger, Lawrence L., Sasakura, Kiyoshi, Nagano, Tetsuo, Hanaoka, Kenjiro, Krijt, Jakub, Stipanuk, Martha H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930650/
https://ncbi.nlm.nih.gov/pubmed/24609271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-014-1700-8
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