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Knockout of the murine cysteine dioxygenase gene results in severe impairment in ability to synthesize taurine and an increased catabolism of cysteine to hydrogen sulfide

Cysteine homeostasis is dependent on the regulation of cysteine dioxygenase (CDO) in response to changes in sulfur amino acid intake. CDO oxidizes cysteine to cysteinesulfinate, which is further metabolized to either taurine or to pyruvate plus sulfate. To gain insight into the physiological functio...

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Detalhes bibliográficos
Main Authors: Ueki, Iori, Roman, Heather B., Valli, Alessandro, Fieselmann, Krista, Lam, Jimmy, Peters, Rachel, Hirschberger, Lawrence L., Stipanuk, Martha H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191547/
https://ncbi.nlm.nih.gov/pubmed/21693692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00151.2011
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