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Structural basis of regulation and oligomerization of human cystathionine β-synthase, the central enzyme of transsulfuration
Cystathionine β-synthase (CBS) controls the flux of sulfur from methionine to cysteine, a precursor of glutathione, taurine, and H(2)S. CBS condenses serine and homocysteine to cystathionine with the help of three cofactors, heme, pyridoxal-5′-phosphate, and S-adenosyl-l-methionine. Inherited defici...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791738/ https://ncbi.nlm.nih.gov/pubmed/24043838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313683110 |
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