Purification, crystallization and preliminary crystallographic analysis of the full-length cystathionine β-synthase from Apis mellifera

Cystathionine β-synthase (CBS) is a pyridoxal-5′-phosphate-dependent enzyme that catalyzes the first step of the transsulfuration pathway, namely the condensation of serine with homocysteine to form cystathionine. Mutations in the CBS gene are the single most common cause of hereditary homocystinuri...

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Main Authors: Oyenarte, Iker, Majtan, Tomas, Ereño, June, Corral-Rodríguez, María Angeles, Klaudiny, Jaroslav, Majtan, Juraj, Kraus, Jan P., Martínez-Cruz, Luis Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2012
Fag:
Crystallization Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515373/
https://ncbi.nlm.nih.gov/pubmed/23143241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112038638
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