Tyr-phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate pyruvate dehydrogenase complex

Mitochondrial pyruvate dehydrogenase complex (PDC) is crucial for glucose homoeostasis in mammalian cells. The current understanding of PDC regulation involves inhibitory serine phosphorylation of pyruvate dehydrogenase (PDH) by PDH kinase (PDK), whereas dephosphorylation of PDH by PDH phosphatase (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fan, Jun, Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chen, Huaibin, Mohammadi, Moosa, Britton, Laura-Mae P., Garcia, Benjamin A., Aleckovic, Masa, Kang, Yibin, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin, Hitosugi, Taro, Seo, Jae Ho, Lonial, Sagar, Gaddh, Manila, Arellano, Martha, Khoury, Hanna J., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943932/
https://ncbi.nlm.nih.gov/pubmed/24486017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.12.026
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados