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Inhibition of p300 impairs Foxp3(+) T-regulatory cell function and promotes anti-tumor immunity
Foxp3(+) T-regulatory (T(reg)) cells maintain immune homeostasis and limit autoimmunity, but can also curtail host immune responses to various types of tumors(1,2). Foxp3(+) T(regs) are therefore considered promising targets to enhance anti-tumor immunity, and efforts are underway to develop approac...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793393/ https://ncbi.nlm.nih.gov/pubmed/23955711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3286 |
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