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Sirtuin-1 Targeting Promotes Foxp3(+) T-Regulatory Cell Function and Prolongs Allograft Survival
Sirtuin 1 (Sirt1), a class III histone/protein deacetylase, is central to cellular metabolism, stress responses, and aging, but its contributions to various host immune functions have been little investigated. To study the role of Sirt1 in T cell functions, we undertook targeted deletions by mating...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067815/ https://ncbi.nlm.nih.gov/pubmed/21199917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01206-10 |
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