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Mbd2 Promotes Foxp3 Demethylation and T-Regulatory-Cell Function

Use of Foxp3-positive (Foxp3(+)) T-regulatory (Treg) cells as potential cellular therapy in patients with autoimmunity, or post-stem cell or -organ transplantation, requires a sound understanding of the transcriptional regulation of Foxp3. Conserved CpG dinucleotides in the Treg-specific demethylati...

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Detalhes bibliográficos
Main Authors: Wang, Liqing, Liu, Yujie, Han, Rongxiang, Beier, Ulf H., Thomas, Rajan M., Wells, Andrew D., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811679/
https://ncbi.nlm.nih.gov/pubmed/23979593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00144-13
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