Essential role of mitochondrial energy metabolism in Foxp3(+) T-regulatory cell function and allograft survival

Conventional T (Tcon) cells and Foxp3(+) T-regulatory (Treg) cells are thought to have differing metabolic requirements, but little is known of mitochondrial functions within these cell populations in vivo. In murine studies, we found that activation of both Tcon and Treg cells led to myocyte enhanc...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Beier, Ulf H., Angelin, Alessia, Akimova, Tatiana, Wang, Liqing, Liu, Yujie, Xiao, Haiyan, Koike, Maya A., Hancock, Saege A., Bhatti, Tricia R., Han, Rongxiang, Jiao, Jing, Veasey, Sigrid C., Sims, Carrie A., Baur, Joseph A., Wallace, Douglas C., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447222/
https://ncbi.nlm.nih.gov/pubmed/25681462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268409
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