Two Histone/Protein Acetyltransferases, CBP and p300, Are Indispensable for Foxp3(+) T-Regulatory Cell Development and Function

T-regulatory (Treg) cells are important to immune homeostasis, and Treg cell deficiency or dysfunction leads to autoimmune disease. A histone/protein acetyltransferase (HAT), p300, was recently found to be important for Treg function and stability, but further insights into the mechanisms by which p...

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Publicado no:Mol Cell Biol
Main Authors: Liu, Yujie, Wang, Liqing, Han, Rongxiang, Beier, Ulf H., Akimova, Tatiana, Bhatti, Tricia, Xiao, Haiyan, Cole, Philip A., Brindle, Paul K., Hancock, Wayne W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386456/
https://ncbi.nlm.nih.gov/pubmed/25154413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00919-14
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