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FOXP3(+) regulatory T cell development and function require histone/protein deacetylase 3
Treg dysfunction is associated with a variety of inflammatory diseases. Treg populations are defined by expression of the oligomeric transcription factor FOXP3 and inability to produce IL-2, a cytokine required for T cell maintenance and survival. FOXP3 activity is regulated post-translationally by...
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| 發表在: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362235/ https://ncbi.nlm.nih.gov/pubmed/25642770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77088 |
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