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FOXP3(+) regulatory T cell development and function require histone/protein deacetylase 3
Treg dysfunction is associated with a variety of inflammatory diseases. Treg populations are defined by expression of the oligomeric transcription factor FOXP3 and inability to produce IL-2, a cytokine required for T cell maintenance and survival. FOXP3 activity is regulated post-translationally by...
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| Pubblicato in: | J Clin Invest |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362235/ https://ncbi.nlm.nih.gov/pubmed/25642770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77088 |
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