Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

The proprotein convertases (PCs) furin, PC5/6, and PACE4 exhibit unique and/or complementary functions. Their knock-out (KO) in mice resulted in strong and specific phenotypes demonstrating that, in vivo, these PCs are unique and essential during development. However, they also exhibit redundant fun...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Essalmani, Rachid, Susan-Resiga, Delia, Chamberland, Ann, Asselin, Marie-Claude, Canuel, Maryssa, Constam, Daniel, Creemers, John W., Day, Robert, Gauthier, Dany, Prat, Annik, Seidah, Nabil G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Protein Synthesis and Degradation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772187/
https://ncbi.nlm.nih.gov/pubmed/23918928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.501304
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