Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

The proprotein convertases (PCs) furin, PC5/6, and PACE4 exhibit unique and/or complementary functions. Their knock-out (KO) in mice resulted in strong and specific phenotypes demonstrating that, in vivo, these PCs are unique and essential during development. However, they also exhibit redundant fun...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Essalmani, Rachid, Susan-Resiga, Delia, Chamberland, Ann, Asselin, Marie-Claude, Canuel, Maryssa, Constam, Daniel, Creemers, John W., Day, Robert, Gauthier, Dany, Prat, Annik, Seidah, Nabil G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2013
Ämnen:
Protein Synthesis and Degradation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772187/
https://ncbi.nlm.nih.gov/pubmed/23918928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.501304
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk