Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis

During chemotaxis, activation of the small guanosine triphosphatase Rac is spatially regulated to organize the extension of membrane protrusions in the direction of migration. In neutrophils, Rac activation is primarily mediated by DOCK2, an atypical guanine nucleotide exchange factor. Upon stimulat...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Nishikimi, Akihiko, Fukuhara, Hideo, Su, Wenjuan, Hongu, Tsunaki, Takasuga, Shunsuke, Mihara, Hisashi, Cao, Qinhong, Sanematsu, Fumiyuki, Kanai, Motomu, Hasegawa, Hiroshi, Tanaka, Yoshihiko, Shibasaki, Masakatsu, Kanaho, Yasunori, Sasaki, Takehiko, Frohman, Michael A., Fukui, Yoshinori
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761877/
https://ncbi.nlm.nih.gov/pubmed/19325080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170179
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi