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Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis
During chemotaxis, activation of the small guanosine triphosphatase Rac is spatially regulated to organize the extension of membrane protrusions in the direction of migration. In neutrophils, Rac activation is primarily mediated by DOCK2, an atypical guanine nucleotide exchange factor. Upon stimulat...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761877/ https://ncbi.nlm.nih.gov/pubmed/19325080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170179 |
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