Molecular Mechanism of Suppression of Testicular Steroidogenesis by Proinflammatory Cytokine Tumor Necrosis Factor Alpha

Tumor necrosis factor alpha (TNF-α) has been demonstrated to inhibit steroidogenesis in Leydig cells at the transcriptional level of steroidogenic enzymes. However, the molecular mechanism of this observed gene repression is not well understood. We now demonstrate that nuclear factor κB (NF-κB) acti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hong, Cheol Yi, Park, Jin Hee, Ahn, Ryun Seop, Im, Suhn Young, Choi, Hueng-Sik, Soh, Jaemog, Mellon, Synthia H., Lee, Keesook
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC371106/
https://ncbi.nlm.nih.gov/pubmed/15024051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.7.2593-2604.2004
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