Transforming Growth Factor-β1 Signaling Represses Testicular Steroidogenesis through Cross-Talk with Orphan Nuclear Receptor Nur77

Transforming growth factor- β1 (TGF-β1) has been reported to inhibit luteinizing hormone (LH) mediated-steroidogenesis in testicular Leydig cells. However, the mechanism by which TGF-β1 controls the steroidogenesis in Leydig cells is not well understood. Here, we investigated the possibility that TG...

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Главные авторы: Park, Eunsook, Song, Chin-Hee, Park, Jae-Il, Ahn, Ryun-Sup, Choi, Hueng-Sik, Ko, CheMyong, Lee, Keesook
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139307/
https://ncbi.nlm.nih.gov/pubmed/25140527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104812
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