Phosphoenolpyruvate Carboxykinase and Glucose-6-phosphatase Are Required for Steroidogenesis in Testicular Leydig Cells

Cyclic AMP (cAMP) induces steroidogenic enzyme gene expression and stimulates testosterone production in Leydig cells. Phosphoenolpyruvate carboxykinase (PEPCK) is expressed in Leydig cells, but its role has not been defined. In this study, we found that PEPCK and glucose-6-phosphatase (Glc-6-Pase)...

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Main Authors: Ahn, Seung Won, Gang, Gil-Tae, Tadi, Surendar, Nedumaran, Balachandar, Kim, Yong Deuk, Park, Ji Hoon, Kweon, Gi Ryang, Koo, Seung-Hoi, Lee, Keesook, Ahn, Ryun-Sup, Yim, Yong-Hyeon, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516735/
https://ncbi.nlm.nih.gov/pubmed/23074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421552
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