Phosphoenolpyruvate Carboxykinase and Glucose-6-phosphatase Are Required for Steroidogenesis in Testicular Leydig Cells

Cyclic AMP (cAMP) induces steroidogenic enzyme gene expression and stimulates testosterone production in Leydig cells. Phosphoenolpyruvate carboxykinase (PEPCK) is expressed in Leydig cells, but its role has not been defined. In this study, we found that PEPCK and glucose-6-phosphatase (Glc-6-Pase)...

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Dades bibliogràfiques
Autors principals: Ahn, Seung Won, Gang, Gil-Tae, Tadi, Surendar, Nedumaran, Balachandar, Kim, Yong Deuk, Park, Ji Hoon, Kweon, Gi Ryang, Koo, Seung-Hoi, Lee, Keesook, Ahn, Ryun-Sup, Yim, Yong-Hyeon, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516735/
https://ncbi.nlm.nih.gov/pubmed/23074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421552
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