Phosphoenolpyruvate Carboxykinase and Glucose-6-phosphatase Are Required for Steroidogenesis in Testicular Leydig Cells

Cyclic AMP (cAMP) induces steroidogenic enzyme gene expression and stimulates testosterone production in Leydig cells. Phosphoenolpyruvate carboxykinase (PEPCK) is expressed in Leydig cells, but its role has not been defined. In this study, we found that PEPCK and glucose-6-phosphatase (Glc-6-Pase)...

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Bibliografische gegevens
Hoofdauteurs: Ahn, Seung Won, Gang, Gil-Tae, Tadi, Surendar, Nedumaran, Balachandar, Kim, Yong Deuk, Park, Ji Hoon, Kweon, Gi Ryang, Koo, Seung-Hoi, Lee, Keesook, Ahn, Ryun-Sup, Yim, Yong-Hyeon, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
Gene Regulation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516735/
https://ncbi.nlm.nih.gov/pubmed/23074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421552
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