Phosphoenolpyruvate Carboxykinase and Glucose-6-phosphatase Are Required for Steroidogenesis in Testicular Leydig Cells

Cyclic AMP (cAMP) induces steroidogenic enzyme gene expression and stimulates testosterone production in Leydig cells. Phosphoenolpyruvate carboxykinase (PEPCK) is expressed in Leydig cells, but its role has not been defined. In this study, we found that PEPCK and glucose-6-phosphatase (Glc-6-Pase)...

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Détails bibliographiques
Auteurs principaux: Ahn, Seung Won, Gang, Gil-Tae, Tadi, Surendar, Nedumaran, Balachandar, Kim, Yong Deuk, Park, Ji Hoon, Kweon, Gi Ryang, Koo, Seung-Hoi, Lee, Keesook, Ahn, Ryun-Sup, Yim, Yong-Hyeon, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516735/
https://ncbi.nlm.nih.gov/pubmed/23074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421552
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