Phosphoenolpyruvate Carboxykinase and Glucose-6-phosphatase Are Required for Steroidogenesis in Testicular Leydig Cells

Cyclic AMP (cAMP) induces steroidogenic enzyme gene expression and stimulates testosterone production in Leydig cells. Phosphoenolpyruvate carboxykinase (PEPCK) is expressed in Leydig cells, but its role has not been defined. In this study, we found that PEPCK and glucose-6-phosphatase (Glc-6-Pase)...

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Autores principales: Ahn, Seung Won, Gang, Gil-Tae, Tadi, Surendar, Nedumaran, Balachandar, Kim, Yong Deuk, Park, Ji Hoon, Kweon, Gi Ryang, Koo, Seung-Hoi, Lee, Keesook, Ahn, Ryun-Sup, Yim, Yong-Hyeon, Lee, Chul-Ho, Harris, Robert A., Choi, Hueng-Sik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Gene Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516735/
https://ncbi.nlm.nih.gov/pubmed/23074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.421552
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