Expression of MIS in the Testis Is Downregulated by Tumor Necrosis Factor Alpha through the Negative Regulation of SF-1 Transactivation by NF-κB

The expression of Mullerian inhibiting substance (MIS), a key molecule in sex differentiation and reproduction, is tightly regulated. It has been suggested that meiotic germ cells repress MIS expression in testicular Sertoli cells, although the substance responsible for this cell-cell communication...

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Autors principals: Hong, Cheol Yi, Park, Jin Hee, Seo, Kook Heon, Kim, Jin-Man, Im, Suhn Young, Lee, Jae Woon, Choi, Hueng-Sik, Lee, Keesook
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC180915/
https://ncbi.nlm.nih.gov/pubmed/12917325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.17.6000-6012.2003
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