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Structure-based network analysis of an evolved G protein-coupled receptor homodimer interface
Crystallographic structures and experimental assays of human CXC chemokine receptor type 4 (CXCR4) provide strong evidence for the capacity to homodimerize, potentially as a means of allosteric regulation. Even so, how this homodimer forms and its biological significance has yet to be fully characte...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690714/ https://ncbi.nlm.nih.gov/pubmed/23553730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2258 |
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