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Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

Functional crosstalk between G protein-coupled receptors in a homo- or heterodimeric assembly likely involves conformational changes at the dimer interface, but the nature of this interface is not yet established, and the dynamic changes have not yet been identified. We have mapped the homodimer int...

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Detalhes bibliográficos
Main Authors: Guo, Wen, Shi, Lei, Filizola, Marta, Weinstein, Harel, Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287488/
https://ncbi.nlm.nih.gov/pubmed/16301531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508950102
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