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Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface determine activation

Functional crosstalk between G protein-coupled receptors in a homo- or heterodimeric assembly likely involves conformational changes at the dimer interface, but the nature of this interface is not yet established, and the dynamic changes have not yet been identified. We have mapped the homodimer int...

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Main Authors: Guo, Wen, Shi, Lei, Filizola, Marta, Weinstein, Harel, Javitch, Jonathan A.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287488/
https://ncbi.nlm.nih.gov/pubmed/16301531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508950102
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