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G-Protein Coupled Receptors: Advances in Simulation and Drug Discovery
G-protein coupled receptors (GPCRs), the largest family of human membrane proteins, mediate cellular signaling and represent primary targets of about one third of currently marketed drugs. GPCRs undergo highly dynamic structural transitions during signal transduction, from binding of extracellular l...
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| Publicado no: | Curr Opin Struct Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154880/ https://ncbi.nlm.nih.gov/pubmed/27344006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.008 |
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