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G-Protein Coupled Receptors: Advances in Simulation and Drug Discovery
G-protein coupled receptors (GPCRs), the largest family of human membrane proteins, mediate cellular signaling and represent primary targets of about one third of currently marketed drugs. GPCRs undergo highly dynamic structural transitions during signal transduction, from binding of extracellular l...
Sparad:
| I publikationen: | Curr Opin Struct Biol |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154880/ https://ncbi.nlm.nih.gov/pubmed/27344006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.008 |
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