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G-Protein Coupled Receptors: Advances in Simulation and Drug Discovery

G-protein coupled receptors (GPCRs), the largest family of human membrane proteins, mediate cellular signaling and represent primary targets of about one third of currently marketed drugs. GPCRs undergo highly dynamic structural transitions during signal transduction, from binding of extracellular l...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Curr Opin Struct Biol
Päätekijät: Miao, Yinglong, McCammon, J. Andrew
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154880/
https://ncbi.nlm.nih.gov/pubmed/27344006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.06.008
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