Evaluation of methods for modeling transcription-factor sequence specificity

Genomic analyses often involve scanning for potential transcription-factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to model and learn a protein’s binding specificity, but these methods have not been systematically compa...

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Päätekijät: Weirauch, Matthew T., Cote, Atina, Norel, Raquel, Annala, Matti, Zhao, Yue, Riley, Todd R., Saez-Rodriguez, Julio, Cokelaer, Thomas, Vedenko, Anastasia, Talukder, Shaheynoor, Bussemaker, Harmen J., Morris, Quaid D., Bulyk, Martha L., Stolovitzky, Gustavo, Hughes, Timothy R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3687085/
https://ncbi.nlm.nih.gov/pubmed/23354101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2486
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