Diversity and Complexity in DNA Recognition by Transcription Factors

Sequence preferences of DNA-binding proteins are a primary mechanism by which cells interpret the genome. Despite these proteins’ central importance in physiology, development, and evolution, comprehensive DNA-binding specificities have been determined experimentally for few proteins. Here, we used...

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Main Authors: Badis, Gwenael, Berger, Michael F., Philippakis, Anthony A., Talukder, Shaheynoor, Gehrke, Andrew R., Jaeger, Savina A., Chan, Esther T., Metzler, Genita, Vedenko, Anastasia, Chen, Xiaoyu, Kuznetsov, Hanna, Wang, Chi-Fong, Coburn, David, Newburger, Daniel E., Morris, Quaid, Hughes, Timothy R., Bulyk, Martha L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905877/
https://ncbi.nlm.nih.gov/pubmed/19443739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162327
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