Predicting the binding preference of transcription factors to individual DNA k-mers

Motivation: Recognition of specific DNA sequences is a central mechanism by which transcription factors (TFs) control gene expression. Many TF-binding preferences, however, are unknown or poorly characterized, in part due to the difficulty associated with determining their specificity experimentally...

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Detaylı Bibliyografya
Asıl Yazarlar: Alleyne, Trevis M., Peña-Castillo, Lourdes, Badis, Gwenael, Talukder, Shaheynoor, Berger, Michael F., Gehrke, Andrew R., Philippakis, Anthony A., Bulyk, Martha L., Morris, Quaid D., Hughes, Timothy R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666811/
https://ncbi.nlm.nih.gov/pubmed/19088121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn645
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