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Identification of human lineage-specific transcriptional co-regulators enabled by a glossary of binding modules and tunable genomic backgrounds

Transcription factors (TFs) control cellular processes by binding specific DNA motifs to modulate gene expression. Motif enrichment analysis of regulatory regions can identify direct and indirect TF binding sites. Here, we created a glossary of 108 non-redundant TF-8mer “modules” of shared specifici...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Mariani, Luca, Weinand, Kathryn, Vedenko, Anastasia, Barrera, Luis A., Bulyk, Martha L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657590/
https://ncbi.nlm.nih.gov/pubmed/28957653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.06.015
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