Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Most tumors display increased glucose metabolism compared to that of normal tissues. The preferential conversion of glucose to lactate in cancer cells (the Warburg Effect) has been emphasized(1); however, the extent to which metabolic fluxes originating from glucose are utilized for alternative proc...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Locasale, Jason W., Grassian, Alexandra R., Melman, Tamar, Lyssiotis, Costas A., Mattaini, Katherine R., Bass, Adam J., Heffron, Gregory, Metallo, Christian M., Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T., Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I., Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H., Meyerson, Matthew, Richardson, Andrea L, Chin, Lynda, Wagner, Gerhard, Asara, John M, Brugge, Joan S., Cantley, Lewis C., Vander Heiden, Matthew G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677549/
https://ncbi.nlm.nih.gov/pubmed/21804546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.890
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars