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A novel small-molecule inhibitor of 3-phosphoglycerate dehydrogenase
Serine metabolism is likely to play a critical role in cancer cell growth. A recent study reports the identification of a novel small-molecule inhibitor of serine synthesis that targets 3-phosphoglycerate dehydrogenase (PHGDH), the first enzyme of the serine synthesis pathway, and selectively abroga...
Enregistré dans:
| Publié dans: | Mol Cell Oncol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972100/ https://ncbi.nlm.nih.gov/pubmed/27652319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1164280 |
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